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We have developed a novel inverse methodology workflow using Nvidia Modulus’s physics-informed neural operator (PINO) as a fast surrogate to solve the black-oil forward problem together with a modified Bayesian adaptive ensemble Kalman inversion (aREKI) approach parametrized with deep neural network (DNN) exotic priors. The DNN prior used here are the variational convolution autoencoder and a novel mixture of deep neural network experts, and together with the developed aREKI method is optimal for sampling non-Gaussian posterior measures, like situations found in channelized reservoirs. The output from the PINO model is the pressure and water saturation fields, and the inputs are the absolute permeability, effective porosity,time-step,initial pressure & saturation, and source and sink terms. The overall workflow is successful in recovering the unknown channelized absolute permeability & effective porosity field for this synthetic case, using an ensemble of 5,000 members with about 100X speedup to traditional numerical approaches. The workflow is suitable for forward and inverse reservoir uncertainty quantification tasks for rapid reservoir management operational decision strategies.