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This paper presents an enhanced pore pressure prediction model using a modified Eaton’s equation that integrates a depth-sensitive compaction trend, improving accuracy in both shallow and deep offshore wells. Traditional methods often rely on a linear Normal Compaction Trend Line (NCTL), which leads to inaccuracies across variable lithologies and water depths. The new model incorporates a dynamic NCTL ( Equation 10 ) derived from integrating Eaton’s method with Wyllie’s time-average and Athy’s porosity-depth relationships. Validation across 15 wells from six offshore Nile Delta fields demonstrated improved accuracy compared to conventional approaches, particularly in challenging intervals. Case studies from shallow and deepwater wells confirmed its adaptability and reliability. The model offers a universal framework with tunable parameters, enhancing pore pressure prediction across diverse offshore environments, reducing drilling risk, and optimizing mud weight and casing programs. This advancement supports safer, more efficient drilling operations in overpressured and geologically complex settings.