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Depth-domain interpretation of seismic data enhances geological realism but remains affected by uncertainties in velocity models and incomplete well integration. Even with accurate seismic-to-well ties, persistent depth mismatches between migrated seismic horizons and well markers can undermine the reliability of reservoir models and volumetric estimates. To address this issue, we present an automated workflow that vertically adjusts a three-dimensional (3D) Relative Geological Time (RGT) model to well markers. Unlike conventional approaches that adjust individual horizons independently, our method simultaneously calibrates all horizons using a non-rigid vertical deformation derived from radial basis function interpolation of measured depth offsets. This mesh-free technique ensures comprehensive well calibration for any interpreted 3D object (e.g., stratal slices, horizons, geobodies, or fault sets), preserving consistency across seismic, well, and derived property data. We demonstrate the workflow on the K05 3D seismic dataset (offshore Netherlands). Compared to traditional horizon-by-horizon fitting, the global RGT adjustment eliminates local thickness artifacts and slightly increases gross rock volume estimates. By applying a single global deformation, the method minimizes inconsistencies when integrating multi-source data, improving the quality of property models. Supported by rigorous seismic and well interpretations, this approach ensures consistent layer thicknesses and enhanced depth predictions, ultimately refining reservoir characterization.